Front-loading with Homeodomains by Mike Gene

October 20, 2007

 ”As the new data comes , undirected fabl of Darwinian evolution becomes more and more tricky misinformation of the materialism.This article belongs to my most favourite researcher, Mike Gene who works on directed evolutionary processes called front-loading. Here is the latest article on him. You had better visit his site ( the design matrix ) to learn more about the concept of fron t loading.”

Mike GENE

For years, I have been trying to flesh out the conceptualization of front-loading evolution at the origin of life. A working hypothesis has been that the first cells (uni-cellular life forms) were front-loaded with information that would facilitate the evolution of multi-cellular life. One possible candidate for such front-loaded ‘information’ would be the homeodomain proteins. These proteins play essential roles in metazoan development and are considered part of the developmental toolkit as outlined by biologist Sean Carroll.

A few months ago, a study was published that outlines data and arguments that perfectly resonate with my front-loading views. Let’s have a look.

The study is Homeodomain proteins belong to the ancestral molecular toolkit of Eukaryotes, published by French researchers, Romain Derelle, Philippe Lopez, Herve´ Le Guyader, and Michael Manuel. It was published in the June, 2007 issue of Evolution & Development (9:212–219). Feast your eyes on the abstract:

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